Fri Nov 24 2023

16 articles - From Friday Nov 17 2023 to Friday Nov 24 2023

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Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…


Meta-analysis

meta-analyses and systematic reviews


Original articles

RCT, clinical trials, retrospective studies, etc…

Am J Clin Nutr

Infant Milk Formula with Large, Milk Phospholipid-coated Lipid Droplets Enriched in Dairy Lipids Affects Body Mass Index Trajectories and Blood Pressure at School Age: Follow-up of a Randomized Controlled Trial.

Early life feeding of an innovative IMF with large, milk phospholipid-coated lipid droplets enriched with dairy lipids results in a BMI trajectory closer to breastfed infants and a lower blood pressure at school age.

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Life's Essential 8, genetic predisposition, and the risk of incident adult-onset asthma: a prospective cohort study.

Our findings suggested that maintaining optimal CVH should be recommended as a preventive strategy for AOA, regardless of their asthma genetic risks.

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Protein intakes affects erythrocyte glutathione synthesis in young healthy adults in a repeated-measures trial.

A protein intake of 1.0 g·kg -1 ·d -1 maximized GSH synthesis which is in agreement with earlier IAAO-derived protein requirements of 0.93 to 1.2g·kg -1 ·d -1 . These findings suggest that recommendations based on NB (0.66g·kg -1 ·d -1 ) may underestimate protein needs for adequate health. Clinical trials registry # NCT02971046,

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Inflamm Bowel Dis

An Atlas Characterizing the Shared Genetic Architecture of Inflammatory Bowel Disease with Clinical and Behavioral Traits.

The present analysis reveals the shared genetic architecture between multiple traits and IBD, CD, and UC. Understanding the relevance of joint occurrences of IBD with psychiatric diseases may moderate management of these diseases for individuals jointly affected by them.

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Clusters of Disease Activity and Early Risk Factors of Clinical Course of Pediatric Crohn's Disease.

During the first 5 years of follow-up, one-third of children with CD experience a quiescent course. However, another one-third have a moderate-to-severe disease course. Surgery at the diagnosis is related to a quiescent course, while growth impairment and lack of response to induction therapy correlate with more severe disease activity during follow-up.

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Proactive Infliximab Monitoring Improves the Rates of Transmural Remission in Crohn's Disease: A Propensity Score-Matched Analysis.

Proactive optimization of IFX based on trough levels increases the rates of transmural remission in CD.

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The Crohn's Disease Exclusion Diet: A Comprehensive Review of Evidence, Implementation Strategies, Practical Guidance, and Future Directions.

In severe disease, complicated phenotypes, or with extraintestinal involvement, CDED should be considered on a case-by-case basis, according to physician and dietitians' discretion. More studies are warranted to assess the efficacy of CDED in different scenarios.

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J Crohns Colitis

Clinical predictors of early and late endoscopic recurrence following ileocolonic resection in Crohn's disease.

We identified independent clinical predictors of early and late Crohn's disease postoperative endoscopic recurrence. Clinical factors traditionally used for risk stratification failed to predict recurrence and need to be revised.

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Pancreatology

A journey to and with the stars: The pancreatic stellate cell story.

This paper summarises her Palade lecture wherein she reflects on her journey as a medical graduate, an academic and a researcher, with a particular focus on her team's pioneering work on pancreatic stellate cell biology and the role of these cells in health and disease. While there has been much progress in this field with the efforts of researchers worldwide, there is much still to be learned; thus it is a topic with ample scope for innovative research with the potential to translate into better outcomes for patients with pancreatic disease.

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Decreased neutrophil counts prolong inflammation in acute pancreatitis and cause inflammation spillover to distant organs.

Prolonged inflammation was observed in the G-CSF-KO mice. Tissue cleanup by neutrophils during the acute phase of inflammation may influence healing through the chronic phase.

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Factors predictive of hospital length of stay in patients with an index episode of acute necrotizing pancreatitis.

We demonstrate that multiple factors including delayed transfers to hospitals with pancreaticobiliary expertise lead to increased length of hospitalization. We suggest various strategies that can be considered to target those gaps and may have a favorable effect on LOS.

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Impact of preoperative endoscopic procedures on adverse event rates after surgical resection for main-duct and mixed-type intraductal papillary mucinous neoplasms (IPMNs).

Postoperative adverse events were not significantly increased among patients who had ERCP or EUS-FNA before surgical resection for MD- or MT-IPMNs. Endoscopic procedures directly sampling the MD can be safely pursued for diagnostic purposes in selected cases.

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NSAIDs do not reduce severity among post-ERCP pancreatitis patients.

Rectal diclofenac or indomethacin before or after ERCP reduce the overall burden of MSPEP by reducing the pool of PEP from which it can arise. However, the proportion of MSPEP among patients who developed PEP is unaffected. Therefore, NSAIDs prevent initiation of PEP, but do not affect severity among those that develop PEP. Alternative modalities are needed to reduce MSPEP among patients who develop PEP.

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The relationship between observation interval and prognosis in pancreatic cancer concomitant with intraductal papillary mucinous neoplasia.

In OI 6 months or less, the rate of resectable PC was high, however, the rate of early PC was almost the same as that of OI more than 6 months. Approximately 10 % of cases found in the advanced stage with metastasis even if OI 6 months or less.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

J Crohns Colitis

Intestinal Failure: A Small but Imperfectly Phenotyped Complication of Crohn's Disease.

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Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

Inflamm Bowel Dis

The Use of Placebo in Clinical Trials of Inflammatory Bowel Disease.

Pubmed   Journal   ReadQx 


Letters&Replies

Letters to the editors and authors’ replies